Reações adversas com a suplementação de cafeína visando o efeito ergogênico: uma revisão estruturada

Abstract

Caffeine (1,3,7-trimethylxanthine) is a popularly known substance and has been used by athletes worldwide aiming at improving physical performance, being regarded as an effective substance for this purpose. Its ergogenic potential have been testing in physical exercises of different modalities and its mechanisms of action are been related to all systems of the human body. Some adverse effects are linked to the use of this substance, which leads to investigate the exposure of individuals to caffeine and the safe dosage to attain the benefits of its consumption without the occurrence of relevant adverse effects. In an attempt to clarify this questioning, was investigated in the scientific literature, through a structured review of articles, of adequate data on the ergogenic effect of caffeine and the related adverse effects according to a dose. In view of the information collected, was verified that there are few reports of severe adverse effects to consumers using an excess of this substance (≥500mg / day) and that individual sensitivity of the individuals should be taken into account when considering the safe daily dosage of this substance in individuals with low tolerance, serving as a basis for future research. Doses of 3-6mg/kg/day seem to be efficient and not related to an occurrence of relevant adverse effects for athletic performance and for human health.