Efeitos da suplementação do extrato da semente da uva na síndrome metabólica

Abstract

Metabolic syndrome (MS) is characterized as a disorder that can involve pictures of glucose intolerance, insulin resistance, dyslipidemia, hypertension and obesity, factors that contribute to the emergence of diseases. The nutritional intervention plays a key role in the treatment and prevention of the metabolic syndrome, since foods that demonstrate high antioxidant properties (OA), such as grapes, have beneficial effects on lipid profile, blood pressure and glucose levels in the blood, as a result efficacy in the treatment of various metabolic disorders. The grapes, exclusively their seed, have polyphenol compounds derived from various species of plants, and have been described in the literature as relevant to inhibit the risk factors involved in the metabolic syndrome, such as hyperglycemia and dyslipidemia, playing an treatment of elements of MS. For this review, we used interventional, randomized and controlled studies, as well as animal and human model studies, which covered the dates of 2000-2018. Based on this context, the present work aims to investigate and explain, through a review of the literature, the effects of grape seed extract in the treatment of the syndrome and if there were satisfactory results regarding its supplementation in animal models.