Análise das pressões respiratórias máximas em renais crônicos submetidos à hemodiálise e à diálise peritoneal

Abstract

Chronic kidney disease (CKD) is defined by progressive and irreversible abnormalities in the structure and glomerular, tubular and endocrine kidney functions, needing the creation of replacement therapies and causing a gradual loss of functional capacity, reflecting on various systems. Objective: To compare respiratory pressures in patients with CKD on hemodialysis (HD) and peritoneal dialysis (PD), to verify which of these is able to compromising more the respiratory muscle strength (RMS). Materials and Methods: 30 subjects participated in the study, divided equally according to their dialysis modality. Maximal inspiratory pressure (MIP) and maximal expiratory pressure (MEP) were assessed by manovacuometry. Statistical analysis was performed using the t test for paired samples, t test for mean differences, ANOVA, ANCOVA and Pearson correlation. The significance level was set at p ≤ 0,05. Results: The study found significant differences between the values of MIP and MEP in the two dialysis modalities, compared to predicted values for the Brazilian healthy population. However, no significant difference in the values of MIP and MEP of HD and PD in the comparison between groups. Conclusion: Patients with CKD undergoing HD and PD showed no statistically significant difference in MIP and MEP. Therefore, the RMS is not a preponderant factor in the modality choice. Nevertheless, both groups showed significant reduction in MIP and MEP in relation to normal reference values, which may reflect a loss in physical and function performances.